منابع مشابه
Ignoring the elephant in the room: a neural circuit to downregulate salience.
How do we ignore stimuli that are salient but irrelevant when our task is to select a lower salient stimulus? Since bottom-up processes favor high saliency, detection of a low-salient target in the presence of highly salient distractors requires top-down attentional guidance. Previous studies have demonstrated that top-down attention can modulate perceptual processing and also that the control ...
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Addiction involves alterations in multiple brain regions that are associated with functions such as memory, motivation and executive control. Indeed, it is now well accepted that addictive drugs produce long-lasting molecular and structural plasticity changes in corticostriatal-limbic loops. However, there are brain regions that might be relevant to addiction other than the prefrontal cortex, a...
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A new study by Ito and colleagues on page 7 may help explain why patients with a severe lung disease called chronic obstructive pulmonary disease (COPD) fail to respond to steroid treatment. Ito and colleagues show that steroids require the enzyme HDAC2 (histone deacetylase 2) to block the inflammatory transcription factor NF-κB. In patients with COPD, HDAC2 activity is reduced, rendering cells...
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In 1947, Paul Beeson showed that rabbits repeatedly injected with certain bacteria eventually become resistant to the bacteria's fever-provoking effects-a phenomenon known as endotoxin tolerance.
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Human-elephant conflict (HEC) threatens the survival of endangered Asian elephants (Elephas maximus). Translocating "problem-elephants" is an important HEC mitigation and elephant conservation strategy across elephant range, with hundreds translocated annually. In the first comprehensive assessment of elephant translocation, we monitored 16 translocations in Sri Lanka with GPS collars. All tran...
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ژورنال
عنوان ژورنال: Western Journal of Medicine
سال: 2001
ISSN: 0093-0415
DOI: 10.1136/ewjm.175.3.212